Not medical advice. Selank is a research compound. This guide does not provide dosing, diagnosis, therapy recommendations, or claims about effects in humans.
Selank is listed in our catalogue under “Cognitive / Neuro.” In scientific publications it is discussed in technical language; this page translates the general themes into everyday wording while staying faithful to research-only framing.
One-paragraph overview from our research datasheet — still scientific, but faster to read than the full mechanism list below.
Selank is a synthetic tuftsin-derived heptapeptide anxiolytic that allosterically modulates GABAA receptors and upregulates hippocampal BDNF expression.
Peer-reviewed literature typically discusses Selank in specific experimental settings. The points below reflect how the scientific community frames this compound—not as health claims, but as the research questions being asked.
Research vs. personal use: Literature describes experiments in controlled lab and animal models. This is distinct from any real-world use; our products are for laboratory research only.
Cognitive-related peptides are explored for stress-response pathways, neuronal signalling, and behaviour in animal models -not as treatments for human brain conditions.
Our datasheet lists mechanistic themes observed in preclinical work. These are research endpoints, not health claims. They help scientists understand and compare pathways.
Storage requirements: Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation. · Learn best practices in our detailed storage guide.
Research dosing context: Literature typically discusses 250–500 μg intranasal; 150–300 μg subcutaneous · Once daily intranasal (0.15% solution, 2–3 drops per nostril) · Complete plasma clearance within 10 minutes post-administration. C-terminal Pro-Gly-Pro extension substantially extends biological activity duration versus native tuftsin (t½ seconds). Intranasal route preferred for non-invasive CNS delivery. Metabolized rapidly in the liver and eliminated via renal excretion. Russian clinical doses: 150–300 μg intranasally, with anxiolytic effects observed within 10–15 minutes of administration.
Preparation steps: Follow our detailed reconstitution guide, use the calculator tool for volume confirmation, and always verify purity with the COA reading guide.
Russian clinical trials compared Selank directly with medazepam and found comparable anxiolytic efficacy. The key differences are the side effect profiles - Selank does not produce sedation, amnesia, dependence, or withdrawal, which are all common with benzodiazepines. It also adds neurotrophic BDNF support that benzodiazepines lack.
No - it is an allosteric modulator rather than a direct agonist. It alters the affinity of the GABAA receptor for endogenous ligands (including GABA itself and endogenous benzodiazepine-like compounds) rather than binding the receptor as an agonist directly. That mechanistic difference is part of why it avoids the classic benzodiazepine side effect profile.
Both are Russian heptapeptides with Pro-Gly-Pro stabilising tails and intranasal delivery, and they share several effects like BDNF elevation and monoamine modulation. Selank emphasises anxiolysis and mood stabilisation; Semax emphasises cognition and neuroprotection. They are often used together in research protocols covering both dimensions.
Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The Pro-Gly-Pro tail gives Selank much better stability than parent tuftsin (which has a half-life measured in seconds), but standard peptide handling still applies.
No, and no. This article is educational only. We do not provide dosing, medical recommendations, or health claims. Our products are sold strictly for laboratory research, not for personal use of any kind.
Open the shop listing via “View product details.” There you will see batch specs, the Certificate of Analysis (COA), concentration, purity grade, and available SKUs with current pricing.
Other compounds researchers often read about alongside Selank.
Primary literature and registries for Selank, plus mainstream coverage of the peptide category. Research use only - not medical advice.
Databases & literature:
Peptides in the news:
Access concentration, batch info, variants, and current pricing on our shop.
Also known as: Selank, TP-7, Selanc, TKPRPGP, Tuftsin Analogue, Thr-Lys-Pro-Arg-Pro-Gly-Pro, Selank Acetate, PL14736