Not medical advice. Kisspeptin is a research compound. This guide does not provide dosing, diagnosis, therapy recommendations, or claims about effects in humans.
Kisspeptin is listed in our catalogue under “Hormone / Fertility.” In scientific publications it is discussed in technical language; this page translates the general themes into everyday wording while staying faithful to research-only framing.
One-paragraph overview from our research datasheet — still scientific, but faster to read than the full mechanism list below.
Kisspeptin-10 is the C-terminal decapeptide of the KISS1 gene product that activates KISS1R (GPR54) on hypothalamic GnRH neurons, the master upstream trigger of the reproductive (HPG) axis.
Peer-reviewed literature typically discusses Kisspeptin in specific experimental settings. The points below reflect how the scientific community frames this compound—not as health claims, but as the research questions being asked.
Research vs. personal use: Literature describes experiments in controlled lab and animal models. This is distinct from any real-world use; our products are for laboratory research only.
Compounds in this family are frequently studied in models of tissue injury, wound closure, and how cells reorganise after damage. Research looks at cell movement, blood-vessel support, and inflammatory balance -not at replacing medical care.
Our datasheet lists mechanistic themes observed in preclinical work. These are research endpoints, not health claims. They help scientists understand and compare pathways.
Storage requirements: Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation. · Learn best practices in our detailed storage guide.
Research dosing context: Literature typically discusses Reported only as published research context — not a recommendation · Study- and route-dependent (bolus or continuous infusion in published kisspeptin pharmacology) · Kisspeptin-10 has a short circulating half-life (on the order of minutes); kisspeptin-54 is longer-acting. Published research doses are highly model-, species-, and route-specific and are not reproduced here as a protocol. Research use only — not for human use.
Preparation steps: Follow our detailed reconstitution guide, use the calculator tool for volume confirmation, and always verify purity with the COA reading guide.
A GnRH agonist acts directly on the pituitary side of the cascade. Kisspeptin acts one step earlier, on the GnRH neurons in the hypothalamus that release GnRH in the first place. That upstream position is why researchers use it to study the natural, physiological control of the reproductive axis rather than overriding it.
Kisspeptin-54 (metastin) is the full-length peptide; kisspeptin-10 is its C-terminal ten-amino-acid fragment. Both bind the same KISS1R receptor through the shared C-terminal sequence. Kisspeptin-10 is shorter and shorter-acting (a half-life of minutes), while kisspeptin-54 circulates longer.
The KISS1 gene was originally discovered as a metastasis-suppressor gene, and its product was named metastin before the reproductive role of its receptor (GPR54/KISS1R) was understood. Kisspeptin and metastin refer to the same molecule.
Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. As with most research peptides, avoid repeated freeze-thaw cycles of the reconstituted solution.
No, and no. This article is educational only. We do not provide dosing, medical recommendations, or health claims. Our products are sold strictly for laboratory research, not for personal use of any kind.
Open the shop listing via “View product details.” There you will see batch specs, the Certificate of Analysis (COA), concentration, purity grade, and available SKUs with current pricing.
Primary literature and registries for Kisspeptin, plus mainstream coverage of the peptide category. Research use only - not medical advice.
Databases & literature:
Peptides in the news:
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Also known as: Kisspeptin-10, KP-10, Metastin (45-54), KISS1, GPR54/KISS1R Agonist, Metastin C-Terminal Decapeptide