Not medical advice. Epitalon is a research compound. This guide does not provide dosing, diagnosis, therapy recommendations, or claims about effects in humans.
Epitalon is listed in our catalogue under “Metabolic / Longevity.” In scientific publications it is discussed in technical language; this page translates the general themes into everyday wording while staying faithful to research-only framing.
One-paragraph overview from our research datasheet — still scientific, but faster to read than the full mechanism list below.
Epitalon (AEDG) is a synthetic tetrapeptide telomerase activator that upregulates hTERT expression to elongate telomeres in human somatic cells.
Peer-reviewed literature typically discusses Epitalon in specific experimental settings. The points below reflect how the scientific community frames this compound—not as health claims, but as the research questions being asked.
Research vs. personal use: Literature describes experiments in controlled lab and animal models. This is distinct from any real-world use; our products are for laboratory research only.
Researchers study these compounds for mitochondrial function, nutrient sensing, and cellular energy stress responses -often in ageing or metabolic disease models.
Our datasheet lists mechanistic themes observed in preclinical work. These are research endpoints, not health claims. They help scientists understand and compare pathways.
Storage requirements: Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation. · Learn best practices in our detailed storage guide.
Research dosing context: Literature typically discusses 5–10 mg subcutaneous injection · Once daily for 10–20 consecutive days, repeated every 4–6 months · Formal human pharmacokinetic parameters (t½, Vd, bioavailability) have not been published. As a tetrapeptide (MW 390.35 Da), Epitalon is subject to rapid peptidase hydrolysis releasing constituent amino acids. Subcutaneous and intraperitoneal routes are standard in published animal protocols. BBB penetration has been demonstrated in animal models. Oral bioavailability is not characterized.
Preparation steps: Follow our detailed reconstitution guide, use the calculator tool for volume confirmation, and always verify purity with the COA reading guide.
Yes - the two spellings refer to the same tetrapeptide (Ala-Glu-Asp-Gly). "Epitalon" and "Epithalon" are interchangeable transliterations of the Russian name. You will also see "Epithalone" and "AEDG peptide" in the literature, all referring to the same compound.
That is a longevity research question that has not been definitively answered. The cell culture telomere-elongation data is clear, and there are animal studies showing increased maximum lifespan. Human longevity data is limited to small studies and anecdotal reports. It remains a research compound, not a validated longevity therapy.
The most commonly used protocol is 5-10 mg subcutaneous injection once daily for 10-20 consecutive days, followed by a 4-6 month rest period before the next cycle. This pulse-then-rest pattern mirrors the original Russian animal study protocols and is designed to avoid receptor desensitisation.
Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The tetrapeptide is small and simple, so it tolerates standard peptide handling well within the normal usage window.
No, and no. This article is educational only. We do not provide dosing, medical recommendations, or health claims. Our products are sold strictly for laboratory research, not for personal use of any kind.
Open the shop listing via “View product details.” There you will see batch specs, the Certificate of Analysis (COA), concentration, purity grade, and available SKUs with current pricing.
Other compounds researchers often read about alongside Epitalon.
Primary literature and registries for Epitalon, plus mainstream coverage of the peptide category. Research use only - not medical advice.
Databases & literature:
Peptides in the news:
Access concentration, batch info, variants, and current pricing on our shop.
Also known as: Epitalon, Epithalon, Epithalone, AEDG Peptide, Ala-Glu-Asp-Gly, Epitalon Tetrapeptide, Khavinson Peptide, Epithalamin Synthetic Analog